Anticancer Drugs Gemcitabine, Letrozole, and Tamoxifen in Municipal Wastewater and Their Photodegradation in Laboratory-Scale UV Experiments
نویسندگان
چکیده
Abstract The occurrence of three anticancer drugs (gemcitabine, letrozole, tamoxifen) was studied in wastewater samples from two local treatment plants (WWTPs) Finland. Studied pharmaceuticals were selected, as are potential to cause adverse effects on organisms even at low concentrations, but they seldom included the analysis emerging contaminants. concentration determined by liquid chromatography-triple quadrupole mass spectrometer (LC–MS/MS). Tamoxifen and letrozole detected influent ranging 0.5 5.0 ng/L, respectively. Letrozole effluent a up 2.4 ng/L. has been only once before, lower 0.28 Gemcitabine not any samples. UV irradiation is used many disinfect effluent. Such tertiary might degrade also these potentially harmful and, therefore, photodegradation chosen laboratory-scale experiments. showed high degradation rates, 94% spiked with fluence 4830 mJ/cm 2 98% pure water 2520 , lowest rates 24% 34% water, rate level typical for disinfection stage 37% tamoxifen 5% letrozole. To best authors’ knowledge, this first report show effectiveness
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ژورنال
عنوان ژورنال: Water Air and Soil Pollution
سال: 2022
ISSN: ['0049-6979', '1573-2932']
DOI: https://doi.org/10.1007/s11270-022-05763-x